Our recent study demonstrated that immunizations with nonreplicable MC38 colorectal cancer cells plus a novel recombinant protein adjuvant, the amino-terminus region of dense granule protein 6 (rGRA6Nt) of Toxoplasma gondii (a protozoan parasite), effectively activate the cancer cell-specific CD8+ T cytotoxic cells and inhibit the growth of implanted tumors of the identical cancer cells after its challenge implantation. Here, CD8A is linked to cancer.