KDM6B and glioblastoma: Another study has also confirmed that in glioblastoma cell lines, KDM6B is involved in cell proliferation, migration, and invasion by inducing the expression of SNAI1 (Salminen et al., 2014).In addition, the deletion of Kdm6b enhances antigen presentation, interferon response, and the efficacy of ICI (immune checkpoint inhibitor) immunotherapy in myeloid cells by suppressing immunosuppressive mediators, including Mafb, Socs3, and Sirpa (Goswami et al., 2023).