To investigate the possible implication of the GAKD1297N isoform in the manifestation of LRRK2 G2019S PD, we collected detailed clinical information from a total of 233 L2-PD patients followed at the Movement Disorders Unit of Hospital Clínic in Barcelona and genotyped them for the rs1134921 variant. Here, LRRK2 is linked to Parkinson disease.