To decipher the role of MT CoA biosynthesis in gut tumor growth, we used a dual binary expression system (UAS-Gal4 and LexAop-LexA) to simultaneously induce tumor in the gut and knock down Smvt in the MTs (Gutts>yki[S3A], MTts>SmvtRNAi). The gene discussed is LGALS4; the disease is neoplasm.