In liver fibrosis, it suppresses HSC activation by sponging miR-181b-5p to upregulate PTEN (94), while in hepatocellular carcinoma (HCC), it inhibits tumor progression via miR-9 sequestration and p21 activation, with its downregulation predicting poor patient prognosis (95). The gene discussed is PTEN; the disease is hepatocellular carcinoma.