The DGP and ERS guidelines explicitly name conditions like asthma (cough as asthma equivalent), non-asthmatic eosinophilic bronchitis, upper airway cough syndrome including rhinosinusitis and pharyngolaryngitis, gastro-oesophageal reflux disease (GERD) and ACE inhibitor use as potential triggers for RCC. The gene discussed is ACE; the disease is gastroesophageal reflux disease.