Some of the greatest successes of kinase inhibitors include ABL kinase inhibitors in BCR::ABL1 positive chronic myelogenous leukemia (CML) which transformed CML from a deadly disease curable only by allogeneic stem cell transplant to a chronic disease curable with an oral kinase inhibitor (2). Here, ABL1 is linked to chronic myelogenous leukemia, BCR-ABL1 positive.