Anti-dsDNA was also positive (92 IU/mL; normal: <30 IU/mL), with SSA/Ro60, SSB/La, and SSA/Ro52 all strongly positive (4+), while MPO, PR3, and anti-Scl-70 were negative, findings suggestive of active SLE. This evidence concerns the gene TRIM21 and systemic lupus erythematosus.