Infants with IUGR typically present with low birth weight and altered morphological features of allometric organ growth and are prone to perinatal complications that affect multiple body systems (18).Klotho is highly expressed in the brain, the kidney, and parathyroid and pituitary glands, but can also serve as a circulating hormone by its shedding, forming soluble klotho that can be detected in blood, cerebrospinal fluid, and urine. Here, KL is linked to fetal growth restriction.