CPNE4 and acute lymphoblastic leukemia: Notably, several disease-related proteins showed marked elevation in T-ALL, with some exceeding threefold higher abundance in patients compared to healthy individualsfor example, eleven-nineteen lysine-rich leukemia protein (ELL), triggering receptor expressed on myeloid cells 1 (TREM1), cisplatin resistance-associated overexpressed protein (CISOP), X-ray radiation resistance-associated protein 1 (XRRA1), tumor necrosis factor receptor superfamily member 10D (TNFRSF10D), protein S100-A8 (S100A8), and copine-4 (CPNE4).