IL1B and infection: Clec4a2—/— mice experienced no mortality, less weight loss (Supplementary Figure 1A) (area under the curve [AUC]: mean 47.22 vs. 17.51, p = 0.0279), and lower spleen A. fumigatus burden than WT mice (Supplementary Figure 1B; 5 days post infection [dpi] mean 106360 vs. 45259, p = 0.0377), with only IL-1β levels markedly reduced among cytokines (Supplementary Figure 1C).