For CD4+ T cells, the Boruta analyses identified 13 activation-associated proteins with altered fold changes, of which 9 proteins, ADA, TWEAK, CCL19, TGF-α, CASP-8, CSF-1, OSM, TRANCE, and CXCL11, were significantly reduced in the MG group (Figures 3A, B, Supplementary Table 2). The gene discussed is ADA; the disease is myasthenia gravis.