STARD4 and neoplasm: To further investigate the effect of STARD4 knockdown on tumor growth and sensitivity to lenvatinib, the stably STARD4 silencing PLC/PRF/5 cells and control cells were injected into the right flank of nude mice, and the mice were treated daily with physiological saline or lenvatinib (10 mg/kg) when the tumor reached a volume of approximately 20 mm3.