CISD1 and early-onset autosomal dominant Alzheimer disease: These CISD1 coexpressed genes were involved in thermogenesis, Parkinson's disease, prion disease, diabetic cardiomyopathy, non-alcoholic fatty liver disease, chemical carcinogenesis, reactive oxygen species, Huntington disease, amyotrophic lateral sclerosis, and Alzheimer's disease (Fig. 6G).