As shown in Figure 5G, CISD1 mRNA expression was significantly and positively correlated with m1A, m5C, and m6A related RNA modification enzymes in UVM, ACC, OV, KICH, PCPG, PAAD, SKCM, UCEC, COAD, COADREAD, TGCT, WT, STAD, STES, HNSC, LIHC, BLCA, LAML, PRAD, READ, ESCA, BRCA, LUAD, THCA, KIRP, KIRC, KIPAN, and KIRC, suggesting that m1A, m5C, and m6A RNA modifications may contribute to gene expression related to tumor progression in these cancers in which when CISD1 expression increases. This evidence concerns the gene CISD1 and cancer.