Further analysis utilizing SangerBox showed that gain copy number of CISD1 is associated with higher mRNA expression levels of CISD1 in 19 cancer types including CESC, LUAD, BRCA, ESCA, STES (Stomach and Esophageal carcinoma), SARC, KIPAN (Pan-kidney cohort (KICH + KIRC + KIRP), STAD, UCEC, HNSC, KIRC, LUSC, LIHC, THCA, MESO, READ, OV, UCS, BLCA (Fig. 3E), suggesting that CISD1 mRNA expression level is mainly due to the copy-number alterations. Here, CISD1 is linked to carcinoma of esophagus.