Using SangerBox online analysis tools, surprisingly, we found that CISD1 was significantly and positively correlated with cancer stemness indices: DNAss in OV, DLBC, THYM, STAD, and STES (Fig. 5A); EREG-METHss in OV, DLBC, THYM, STAD, SKCM, MESO, PAAD, STES, PRAD, and BRCA (Fig. 5B); DMPss in OV, DLBC, THYM, STAD, LAML, LIHC, STES, and LUAD (Fig. 5C); ENHss in OV, DLBC, LAML, LIHC, STAD, and ESCA (Fig. 5D). Here, EREG is linked to cancer.