Intriguingly, CISD1 was significantly and positively correlated with RNAss in multiple cancer types including DLBC, UCEC, LGG, LUAD, KIRC, GBMLGG, THCA, READ, SARC, BRCA, SKCM, PCPG, LAML, LIHC, KIPAN, COADREAD (colon adenocarcinoma/rectum adenocarcinoma), TGCT, ESCA, HNSC, COAD, LUSC, CESC, KIRP, and OV (Fig. 5E); and EREG.EXPss in READ, DLBC, THYM, ACC, THCA, LAML, COADREAD, PRAD, COAD, TGCT, OV, PAAD, BRCA, LUAD, LIHC, GBM, UCEC, ESCA, STEX, STAD, BLCA, and KIPAN (Fig. 5F). This evidence concerns the gene CISD1 and rectum adenocarcinoma.