AAA was induced using PPE+Pap and BAPN administration, along with ANG II subcutaneous pump to induce hypertension-induced AAA expansion and acute rupture (Figure 3A and Table 1).17,25 Mice subjected to this novel model (NvRM) demonstrated a remarkable acute rupture rate of 93% (13 out of 14 mice), with an average rupture time of 7.4±1.5 days post-AAA induction (Figure 3B). This evidence concerns the gene AGT and hypertensive disorder.