More than 60% of PDA patients displayed anti‐ENO1 antibodies in their sera, especially against two more acidic isoforms with phosphorylated residues,34 and two‐thirds of patients with anti‐ENO1 Ab also had T cells secreting IFN‐γ in response to recombinant ENO1.35 This evidence concerns the gene ENO1 and Patent ductus arteriosus.