Flow cytometry analysis showed reduced surface expression of c-Kit and CD34, markers of leukemic stemness, and similar differentiation effects were observed in KAT6A-TIF2 and KAT6A-NCOA3 leukemia cells, underscoring the broad impact of CBP/P300 inhibition (Additional file 1: Fig. S8D and E). The gene discussed is NCOA2; the disease is leukemia.