Furthermore, pancreatic acinar cell carcinoma (PACC) has also been reported to be correlated with HRD, with a significantly higher prevalence of HR/DDR germline genetic alterations in BRCA1, BRCA2, PALB2, ATM, and CHEK2 in PACC compared with other tumors, among which BRCA2 mutation occurs most frequently [44]. Here, BRCA2 is linked to pancreatic acinar cell carcinoma.