CCL2 and infection: I.t. administration of NS19504 (1.33 mg/kg) at 0 and 24 h following LPS infection reversed not only LPS-induced total BALF cell counts and neutrophil infiltration, CCL-2 secretion, and cytosolic ROS production but also MIP-1α cytokine secretion (Fig. 1k–o), while inhibition of CXCL-10 secretion was slightly short of meeting statistical significance criteria (p = 0.06; Fig. 1p).