TK1 and FORα were significantly increased in prostate cancer patients compared to the control group (mean 28.11pg/ml vs. 15.66 pg/ml, p-value < 0.001) and (median 1686.4 pg/ml vs. 437.2 pg/ml, p-value < 0.001) respectively. Here, TK1 is linked to Familial prostate cancer.