PHLDB2 and gastric cancer: In gastric cancer, NR2F1-AS1 acts as an EMT-inducing lncRNA that enhances cell motility via the miR-29a/VAMP7 axis, activation of AKT3 through miR-190a/PHLDB2, SPI1-mediated transcriptional upregulation of ST8SIA1, and miR-493-5p/MAP3K2 signaling (Fig. 3) [28–31].