Target cells were pre-treated for 16 hours with 100 U/mL (HaCaT) or 1,000 U/mL (HFF-1) of IFN-β or IFN-γ prior to infection at an MOI of 10 or 1 with HSV-1 McKrae propagated from the previously identified cell types. The gene discussed is IFNG; the disease is infection.