This in silico analysis revealed a 10‐fold increase in IL17A expression in samples from people with ulcerative colitis (UC) alongside marked co‐expression of Il17ra with Trpv1 in colon‐projecting DRG neurons in mice, highlighting a likely role for interleukin‐17 (IL‐17) in colonic nociceptor signalling in people with UC. This evidence concerns the gene IL17A and ulcerative colitis.