Although there have been many studies on SNPs about FD-related proteins such as G protein subunit beta 3 (GNB3), solute carrier family 6 member 4 (SLC6A4), and cholecystokinin-1 receptor (CCK-1R) [13-17], no previous studies have investigated SNPs related to R-FD. The gene discussed is SLC6A4; the disease is Fabry disease.