SPINK1 and pancreatitis: Since significant differences were observed in the ratio of abnormal pancreatic enzymes between patients with R-FD and those with FD (Table 3), we compared the distribution of pancreatitis-related genotypes, such as GPRC6A and SPINK1. However, no significant difference was observed in the distribution of GPRC6A and SPINK1 genotypes between the R-FD and FD groups.