<h4>Objective</h4>We assessed whether circulating adipokines are associated with incident fractures in patients with rheumatoid arthritis (RA).<h4>Methods</h4>Three adipokines (adiponectin, leptin, and fibroblast growth factor [FGF]-21) were measured using banked enrollment serum from participants in a longitudinal RA cohort. The gene discussed is LEP; the disease is rheumatoid arthritis.