Many miRNAs critical in regulating trophoblast proliferation, fatty acid biosynthesis, insulin signaling, and inflammatory response, as well as dipeptidyl peptidase IV (DPPIV), which cleaves glucagon‐like polypeptide‐1 (GLP‐1), are altered in EVs from women with GDM (Kandzija et al. 2019; Herrera‐Van Oostdam et al. 2020; Shah et al. 2021; Nair et al. 2018; Gillet et al. 2019). Here, INS is linked to gestational diabetes.