Hypoxanthine-guanine phosphoribosyl transferase (HPRT) deficiency causes hyperuricemia and gout, along with severe neurological disorders, namely, dance athetosis, mental retardation, and self-injurious behavior.[5] In several investigations,[6] young individuals only exhibit gout manifestations, with mild or absent neurological dysfunction. This evidence concerns the gene HPRT1 and gout.