AKT1, a serine/threonine protein kinase from the AKT family, is linked to the PI3K-AKT pathway, influencing cell proliferation, apoptosis, and glucose metabolism.[22,23] This study identified AKT1 as a target of EB’s active ingredients, with GO and KEGG analyses confirming its crucial role in glaucoma treatment. This evidence concerns the gene AKT1 and glaucoma.