CD3 had the greatest heterogeneity (43.3% of patients had consistent expression patterns (low, high) across tissue cores) in all three tumour regions (TC, TF, stromal-predominant tissue cores), while CD20 had the least (85.5); this pattern persisted when considering only TC and TF (CD3: 63.5%, CD20: 88.5%) (Table S5). Here, TF is linked to neoplasm.