For instance, LRP1 (PoPS Score Overall: 3.67, MO: 0.80), a lipoprotein receptor involved in blood-brain barrier integrity, and CFDP1 (PoPS Score Overall: 0.33, MO: 0.42), a chromatin modifier, were recurrently linked to both Overall migraine and MO, suggesting convergent mechanisms in neurovascular and epigenetic regulation. Here, LRP1 is linked to migraine disorder.