Similar findings were observed for spinal cord (ALS versus non-ALS fc = 0.63, unadjusted p = 0.029; ALS versus control fc = 0.55, unadjusted p = 0.160; ALS versus AD fc = 0.62, unadjusted p = 0.039; there was insufficient data for ALS versus PD as TDP-43 was only detected in a subset of PD samples; Fig. 1A). Here, TARDBP is linked to amyotrophic lateral sclerosis.