To further demonstrate the role of CXCL1 in promoting HPI gastritis, we divided the gastritis samples from the three datasets into a CXCL1 low-expression (CXCL1-Low) group and a CXCL1 high-expression (CXCL1-High) group based on CXCL1 expression levels, and performed differential analysis. This evidence concerns the gene CXCL1 and hyperprolinemia type 1.