The gene transcripts with the greatest number of shared correlations with PRRs across all three infections were PLAUR (with TLR2, RIG-I, LGP2) and SERPING1 (with TLR5, RIG-I, MDA5, and LGP2) (Fig 6A, and S17, S18, and S19 Tables). This evidence concerns the gene IFIH1 and infection.