Specifically, in MSI colorectal cancers, immune ESTIMATE, HAVCR2 (TIM-3), CD274 (PD-L1), LAG3 (LAG-3), and PDCD1 (PD-1) each showed significant inverse correlations with GALNT7 expression across the three cohorts (Fig. 2J–L; Supplementary Table S5). This evidence concerns the gene LAG3 and colorectal cancer.