Intriguingly, and consistent with the findings from transcriptomic datasets (Fig. 2J–M), dMMR/MSI colorectal cancers with GALNT7-High expression exhibited a significantly lower frequency of tumor cell PD-L1 positivity (23.8%) compared with GALNT7-Low dMMR/MSI colorectal cancers (58.8%; Fig. 3J). Here, CD274 is linked to colorectal cancer.