The predictive value evaluation of pCR also showed that the elastic modulus value, Ki-67 expression level and molecular subtypes all had a degree of predictive value for postoperative pCR in patients with early BC (p < 0.05), and the combination of the three had the highest predictive value, with an AUC of 0.922 (95% CI: 0.871, 0.934), a sensitivity of 88.41% and a specificity of 87.42%. The gene discussed is MKI67; the disease is breast cancer.