To explore whether hsa_circ_00 26782 inhibited keloid growth in vivo by promoting p‐Ser142 of CREB1, we generated CREB1‐Ser142A non‐phosphorylated mutant[27, 55] in hsa_circ_0026782‐overexpression (OE) and CREB1 knockout (CREB1‐KO) hKFs (Figure9A). This evidence concerns the gene CREB1 and keloid.