Compared with the EV group, overexpression of hsa_circ_00 26782 significantly suppressed luciferase activity from both LDLR and DUSP9 (Figure 10L), further supporting that hsa_circ_00 26782 inhibited CREB1‐mediated transcription of downstream genes, thereby contributing to the suppression of keloids. The gene discussed is LDLR; the disease is keloid.