The results revealed that white blood cell count, neutrophil count, lymphocyte count, D-dimer, urea, NT-ProBNP, high-sensitivity troponin T, SII, SIRI, NLR, PLR, LDL, total cholesterol, arrhythmias, and lower extremity venous thrombosis were significantly associated with AECOPD with PTE. Here, NPPB is linked to cardiac arrhythmia.