Multivariate logistic regression analysis showed that tumor max length (OR [odds ratio] = 1.455 [1.108–1.826], p = 0.018), tumor number (OR = 1.500 [1.187–1.942], p < 0.001), AFP (OR = 1.322 [1.082–1.916], p < 0.001), PVTT (OR = 1.788 [1.365–2.282], p < 0.001), and smoking history (OR = 2.089 [1.496–3.281], p < 0.001) were significant factors (Table S5). The gene discussed is AFP; the disease is neoplasm.