TPO and myeloproliferative neoplasm: As we observed a significant improvement in BM fibrosis, splenomegaly, and monocytosis in the TPO‐induced PMF model, a robust model for MPN associated with fibrosis (Figure 3), we next sought to validate these findings in a JAK2V617F‐induced murine model of MPN/PMF as a highly patient‐relevant model.