TNFSF11 and obesity due to melanocortin 4 receptor deficiency: The relative expression of RANKL protein was significantly different between the obesity group [(0.70 ± 0.20)] and the non-obesity group [(0.58 ± 0.23)] (T = −2.657, P = 0.021), and the expression of RANKL mRNA was also significantly different between the obesity group [(1.31 ± 0.64)] and the non-obesity group [(1.06 ± 0.37)] (T = −2.144, P = 0.035), as shown in Table 4 and Figure 1.