The evolution of themes over time is visualized using the R package “bibliometrix.” In Figure 10A, we can see that the research topics of ferroptosis in gliomas from 2015 to 2023 are focused on “glioblastoma,” “autophagy,” “bioinformatics” and “oxidative stress.” The research topics in 2024–2025 will focus on “glioblastoma,” “incRNA,” “immunotherapy,” “gpx4,” and “radiotherapy.” This evidence concerns the gene GPX4 and central nervous system cancer.