TRPS1 and breast carcinoma: Baban et al compared breast cancer pleural effusion specimens and fine needle aspiration specimens from mesotheliomas and confirmed that TRPS1 was more specific than GATA3 in confirming breast origin, as both markers were 100% positive in pleural effusion, but there was a significant difference in positivity rates in mesotheliomas (5% vs. 84%) [26].