This association was particularly evident among males (OR = 0.48, 95% CI: 0.25–0.93), patients with a history of hypertension (OR = 0.48, 95% CI: 0.24–0.97), patients with dyslipidemia (OR = 0.52, 95% CI: 0.27–0.99), and those without the angiotensin-converting enzyme inhibitors/angiotensin receptor blockers (ACEI/ARB) use (OR = 0.55, 95% CI; 0.31–0.99). This evidence concerns the gene ACE and metabolic syndrome.