However, the percentage of intermediate monocytes with intracellular IL-10 expression in MLR-high CLL patients was significantly higher in the ZAP-70+ group compared to the ZAP-70− group (median, IQR, 10.55, 12.47–9.41 vs. 7.78, 9.47–3.98; p=0.0303) (Figure 9(b)) and in the CD38+ group compared to the CD38− group (median, IQR, 8.42, 10.56–3.62 vs. 6.14, 8.12–4.28; p=0.0381) (Figure 9(e)). This evidence concerns the gene ZAP70 and B-cell chronic lymphocytic leukemia.