APOL1 and chronic kidney disease: In this study, using data from the Atherosclerosis Risk in Communities (ARIC) Study, healthy Black individuals aged 45–64 years with high-risk APOL1 genotypes and an eGFR >80 mL/min showed no additional risk for developing ESKD, proteinuria, or CKD 3a and higher compared to the low-risk APOL1 group over 25 years of follow-up (8).