PIEZO1 and bacterial infectious disease: Upon bacterial infection or lipopolysaccharide (LPS) stimulation, activation of Piezo1 induces Ca2+ influx, which subsequently triggers the phosphorylation of calcium/calmodulin-dependent protein kinase II (CaMKII) and the Hippo pathway kinases MST1 and MST2 (mammalian STE20-like protein kinases 1 and 2).