FASLG and autoimmune polyendocrinopathy: For this reason, its inclusion in the aPL detection profiles in patients with APS symptoms would help in the management of patients who are currently considered to have “seronegative antiphospholipid syndrome.” Although aPS/PT should not be used to replace LA, the evaluation of these antibodies might be a valuable diagnostic tool in patients with gestational morbidity when classic aPL or LA is negative or inconsistently positive.