EGFR and systemic lupus erythematosus: KEGG pathway analysis revealed that the differential expression of circRNAs was associated with the ErbB signaling pathway, phosphatidylinositol signaling system, inositol phosphate metabolism, and sphingolipid signaling pathways across different SLE severity groups, suggesting that circRNAs may play a role in metabolic processes related to inositol phosphate metabolism.