In esophageal carcinoma, the expression of the lncRNA AGAP2-AS1 increases, and AGAP2-AS1 can bind to miR-195-5p, resulting in a reduction in the content of FOSL1, a target gene of miR-195-5p, which then promotes the invasion and metastasis of cancer or inhibits apoptosis (100). The gene discussed is AGAP2; the disease is carcinoma of esophagus.