LARC – locally advanced rectal cancer; SD – standard deviation; HDL – high–density lipoprotein; LDL– low–density lipoprotein;CRP – C-reactive protein; CEA – carcinoembryonic antigen; CA 19-9 – carbohydrate antigen 19-9; CA 72-4 – tumour-associatedglycoprotein 72; CA 15-3 – cancer antigen 15-3; nCRT – neoadjuvant chemoradiotherapy; RCRG – Rectal Cancer RegressionGrade. Here, CEACAM5 is linked to rectal cancer.